Northern Scotland According to one study, the incidence of Huntington’s disease is the highest in the world, with diagnoses increasing by nearly 50% over the last 30 years.
Researchers at the University of Aberdeen have found that within the NHS Grand Pian region, the number of people with disease-causing genetic defects and prominent symptoms has skyrocketed by 46% since 1984.
Throughout the region, 14.6 per 100,000 people have a diagnosis and prominent symptoms. This is more than five times the prevalence of 2.71 per 100,000 people estimated worldwide.
Thirty-six years ago, the number for the NHS Grand Pian region was 9.94 per 100,000.
A university spokesperson said: health In the board region of northern Scotland, more in the Highlands and less in the Northern Isles than in the Grand Pian.
Huntington’s disease is a complex hereditary neurological condition in which patients walk, talk, eat, and Drink By degrading motor and cognitive facilities. There is currently no cure.
According to a study published in the Journal of Neurology, symptoms usually begin at the age of 30-50 years and usually take 10-25 years from the onset of the disease to death.
Since the gene for Huntington’s disease was identified in 1993, it has been tested to see if more people have it, the study authors said. Each child of a person with Huntington’s disease has a 50% risk of inheriting it.
Researchers have found that high diagnostic rates in both Grand Pian and Highland are due to “underlying genetic susceptibility in ancestral populations, diagnostic benefits in affected families and practitioners (better care and support services). A region with a combination of heightened awareness, and one of the oldest specialized Huntington’s disease research clinics in the world. ”
Professor Zosia Miedzybrodzka of the University of Aberdeen is the lead research author and consultant for the NHS Grand Pian’s Huntington’s Clinic in Northern Scotland.
She states: “In northern Scotland, where levels of Huntington’s disease are known to be high, there has been a 46% increase over the last three decades.
“The emergence of positive genetic testing for people, with or without symptoms, may have contributed to an increase in the number of people diagnosed with Huntington’s disease.
“Even in a country as large as Scotland, the prevalence varies considerably from region to region of the Health Commission.
“This difference can have a significant impact on drug costs and service delivery, especially if expensive and complex therapies are successful.
“Medical services need to collect accurate population-based data by region to inform service plans.”
Alistair Haw, Chief Executive Officer of the Scottish Huntington’s Association, said:
Huntington’s disease: nearly 50% increase in cases in northern Scotland
Source link Huntington’s disease: nearly 50% increase in cases in northern Scotland